Mark P. Farrell

School of Pharmacy - Medicinal Chemistry
Assistant Professor
Primary office:
785-864-1610
Shankel Structural Biology Center
University of Kansas
2030 Becker Drive
Lawrence, Kansas 66047


Summary

Assistant Professor Mark Farrell earned a Ph.D. in synthetic organic chemistry and a bachelor of science in chemistry from the National University Ireland.

Education

Ph.D., Synthetic Organic Chemistry, National University Ireland

B.S., Chemistry, 1st Class honours, National University Ireland

Selected Publications

Influence of acyl groups on glucopyranoside reactivity in Lewis acid promoted anomerizations. Tett. Lett., 2018, 59, 2727-2731.

Herschhorn, A. Gu, C. Moraca, F. Ma, X. Farrell, M. Smith, A. B., Pancera, M. Kwong, P. D., Schön, A. Freire, E. Abrams, C. Blanchard, S. C., Mothes, W. & Sodroski, J. G. (2017). The β20–β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions. Nature Communications, 8(1), 1049. DOI:10.1038/s41467-017-01119-w https://doi.org/10.1038/s41467-017-01119-w

Farrell, M. Melillo, B. & Smith, A. B. (2016). Type II Anion Relay Chemistry: Exploiting Bifunctional Weinreb Amide Linchpins for the One-Pot Synthesis of Differentiated 1,3-Diketones, Pyrans, and Spiroketals. Angew. Chem. Int. Ed, 55, 232-235.

Farrell, M. O'Reilly, C. Venkatrao Jarikote, D. & Murphy, P. V. (2014). Ultrasonic Energy Promoted Allylation to Generate 1-C-(2,3,4,6-Tetra-O-benzyl-α-D-glucopyranosyl)prop-2-ene. Carbohydrate Chemistry: Proven Synthetic Methods, 2.

Breen, E. P., Pilgrim, W. Clarke, K. J., Yssel, C. Farrell, M. Zhou, J. Murphy, P. V., & Porter, R. K. (2013). Lack of Activation of UCP1 in isolated brown adipose tissue mitochondria by glucose-O-ω-modified saturated fatty acids of various chain lengths. J. Chem. Biol, 6, 121-133.

Farrell, M. Zhou, J. & Murphy, P. V. (2013). Regiospecific anomerisation of acylated glycosyl azides and benzoylated disaccharides using TiCl4. Chem. Eur. J, 13, 14836-14851

Gerlach, J. Kilcoyne, M. Farrell, M. Kane, M. & Joshi, L. (2012). Differential release of high mannose structural isoforms by fungal and bacterial endo-β-N-acetylglucosaminidases. Mol. BioSyst, 8, 1472-1481

Kilcoyne, M. Gerlach, J. Farrell, M. Bhavanandan, V. & Joshi, L. (2011). Periodic acid-Schiff’s reagent assay for carbohydrates in a microtiter plate format. Anal. Biochem, 1, 18-26

Selected Awards & Honors


The University of Kansas | Lawrence, KS | April 12 - 14, 2019
Medicinal Chemistry Meeting in Miniature
One of 34 U.S. public institutions in the prestigious Association of American Universities
44 nationally ranked graduate programs.
—U.S. News & World Report
Top 50 nationwide for size of library collection.
—ALA
5th nationwide for service to veterans —"Best for Vets: Colleges," Military Times
KU Today