Dr. Emily Scott is a professor in the Department of Medicinal Chemistry. Her research focuses on understanding how individual human cytochrome P450 (CYP) enzymes perform roles in drug metabolism and physiologically important endogenous processes. Interest in the basic biochemistry and structural biology of these intriguing membrane enzymes overlaps with application of this knowledge to benefit human health and disease treatment. CYP2A enzymes are involved in activation of tobacco procarcinogens into DNA-modifying agents, so inhibitors are of interest for their potential to prevent lung cancer. CYP17A1 is essential in production of steroid hormones that drive prostate cancer proliferation. Interactions of CYPs with their substrates and existing and new inhibitors are probed using a variety of biochemical and structural biology techniques.